WASHINGTON, CMC – On February 26, 2020, Brazil recorded the first case of the coronavirus (COVID-19) in its territory, marking the beginning of the pandemic in Latin America and the Caribbean (LAC).
Since its emergence on December 30, 2019, in Wuhan, China, the SARS-CoV-2 virus has left a devastating trail globally, with 774 million cases and seven million deaths recorded to date. The Americas were brutally hit, accounting for 25 percent of all cases and 43 percent of all deaths, making it the region with the highest number of COVID-19 deaths worldwide.
Over time, the virus has changed and evolved, becoming more transmissible but less lethal. In May last year, the World Health Organization (WHO) declared the end of COVID-19 as a Public Health Emergency of International Concern. Still, infections continue to occur, with more than half a million cases reported worldwide in the last month.
On the fourth anniversary of the arrival of SARS-CoV-2 in the region, virologist Jairo Méndez, the regional advisor on viral diseases at the Pan American Health Organization (PAHO), addressed what he believes the LAC has learned about the virus that causes COVID-19.
“The pandemic left a profound impact at the global and regional levels, the dimensions we still fully understand. A fundamental lesson is the importance of collaboration and solidarity among countries in dealing with crises of this magnitude.
“We recognized the gaps in our preparedness and the need to strengthen our capabilities. We learned to rely on science, which allowed us to develop safe and effective vaccines in record time,” Méndez said.
But he added that health experts have also realized that the virus is highly adaptable and can change rapidly, requiring people to continue to monitor its evolution and explore potential natural reservoirs closely.
“Surveillance networks led by PAHO have been established to monitor the presence of new coronaviruses. Although vaccines continue to be effective, we must remain alert to any changes in the virus and continue to learn about it every day to protect public health,” he said.
Asked what information people have today about the different variants of the SARS-CoV-2 virus and its evolution, Mendez noted that several variants of the SARS-CoV-2 virus have been identified since its emergence, starting with Alpha in late 2020, followed by Gamma and Delta, which had a significant public health impact.
“Subsequently, Omicron emerged in late 2021, classified as a variant of concern due to its rapid spread. Although the virus has continued to evolve, no significant increase in variant severity or mortality has been detected. While several variants, such as JN.1, are currently being monitored, none have characteristics that make them more aggressive or lethal.”
He said the main challenges in controlling the virus in the region have been numerous and significant.
“First, the initial lack of understanding about the virus and how to deal with it was daunting. We did not have the necessary tools to detect and diagnose it effectively. Then, the rapid change of the virus and the emergence of variants posed additional challenges for monitoring and control.
“However, despite these, progress has been made in integrating epidemiological and virological surveillance systems, which enable us to detect and respond more effectively to future threats,” Mendez added.
The PAHO official said that as a region, there have been several achievements in the surveillance and diagnosis of SARS-CoV-2.
“For example, in a very short period, we established a network of laboratories at the regional level capable of rapidly diagnosing the virus, which allowed us to respond quickly. Surveillance systems were rapidly adapted, building on previous experience working with influenza.”
Asked whether COVID-19 can be considered just another flu, Mendez said respiratory viruses, including COVID-19 and influenza, can potentially cause serious harm, especially in vulnerable populations such as the elderly or those with pre-existing medical conditions.
“We cannot underestimate the seriousness of this illness or assume it is just a cold. The need to protect ourselves and be vigilant is crucial, as a significant outbreak could easily overwhelm healthcare systems.
“Influenza, commonly called the flu, is not trivial and can have serious consequences, especially for those most at risk. COVID-19 is still present, and although it has become more predictable, we must always be prepared,” Mendez said.
He warned that the factors that contribute to the emergence of new viruses and pathogens are still present.
“While we cannot predict when or how it will occur, we can be better prepared by maintaining constant vigilance and rapid response preparedness. This underscores the importance of the International Health Regulations and transparency in communication between countries to detect and respond to new threats effectively.
Mendez said PAHO had played a crucial role during the pandemic in several areas, for example, by supporting surveillance of respiratory diseases, facilitating the implementation of diagnostic protocols for COVID-19, and debunking false information.
“In addition, we developed evidence-based clinical guidelines and supported the implementation of vaccination plans. We are focused on strengthening regional capacity to deal with future pandemics, reducing dependence on external inputs, and promoting solidarity among countries to share information and provide mutual support.
“ One lesson learned is that science must guide actions in response to health emergencies, and we hope that confidence in it will grow and that this will happen in the next emergency,” Mendez added.
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